{"id":1081,"date":"2026-09-24T10:00:00","date_gmt":"2026-09-24T10:00:00","guid":{"rendered":"https:\/\/pro-studio.ir\/mahutco\/blog\/preventive-maintenance-hplc-gc\/"},"modified":"2026-09-24T10:00:00","modified_gmt":"2026-09-24T10:00:00","slug":"preventive-maintenance-hplc-gc","status":"publish","type":"post","link":"https:\/\/pro-studio.ir\/mahutco\/blog\/preventive-maintenance-hplc-gc\/","title":{"rendered":"What a Preventive Maintenance Visit Covers on HPLC and GC"},"content":{"rendered":"\n

Preventive maintenance is work done while the chromatograph still runs. The point is to replace what is worn and to find a leak or a restriction before it ruins a sequence. It is not a full method validation, and it is not automatically a calibration certificate.<\/p>\n\n\n\n

This is what a useful visit looks like on an HPLC or a GC. The exact list depends on the model and on how hard the instrument is used.<\/p>\n\n\n\n

Before the visit<\/h2>\n\n\n\n

Agree a window when the system can be stopped. Tell the technician which method must run again before they leave, and which column and mobile phase or gases that method uses. A column left drying out, or a buffer left in a pump over a long shutdown, creates the next fault.<\/p>\n\n\n\n

Have the last good chromatogram available. \u201cIt used to look like this\u201d is more useful than a vague note that sensitivity is down.<\/p>\n\n\n\n

\"Septa,<\/figure>\n\n\n\n

HPLC<\/h2>\n\n\n\n

The technician records the usual pressure at the method flow before changing anything. That number is the reference.<\/p>\n\n\n\n

Typical checks:<\/p>\n\n\n\n

    \n
  • Solvent level, inlet frits, and visible leaks at the pump and column fittings<\/li>\n\n
  • Prime and degas path, if pressure has been unstable<\/li>\n\n
  • Pump seals and check valves if the ripple or a leak says they are due, not on a fixed guess<\/li>\n\n
  • Guard column and inline filters if pressure has crept up<\/li>\n\n
  • Autosampler syringe or needle seat if injections have become short<\/li>\n\n
  • Detector lamp energy or the detector\u2019s own readiness, without opening a flow cell that is not user-serviceable<\/li>\n\n
  • Waste lines, so a quiet leak is not filling a container out of sight<\/li>\n<\/ul>\n\n\n\n

    Consumables are replaced when the check or the service interval says they are worn. A new column is not fitted just because the visit happened. Column changes affect retention and selectivity and belong to the method owner unless the column is damaged.<\/p>\n\n\n\n

    GC<\/h2>\n\n\n\n

    Typical checks:<\/p>\n\n\n\n

      \n
    • Cylinder or generator pressure, and the correct gas on each line<\/li>\n\n
    • Moisture and hydrocarbon traps that are in the service plan<\/li>\n\n
    • Septum and inlet liner, especially after dirty samples<\/li>\n\n
    • Column nuts and ferrules for leaks, without overtightening<\/li>\n\n
    • Syringe condition<\/li>\n\n
    • Detector gases and, on an FID, a stable flame and a plausible baseline at the normal start temperature<\/li>\n\n
    • Split vent and septum purge paths if pressure or sensitivity has been wrong<\/li>\n<\/ul>\n\n\n\n

      The technician does not hunt for a gas leak with a flame. A leak shutdown or the smell of gas ends the user-level work.<\/p>\n\n\n\n

      What you should receive<\/h2>\n\n\n\n

      A short record: instruments covered, what was inspected, what was replaced, pressures or detector state after the work, and anything that should be planned before the next visit. If a check standard was run, the conditions of that run should be written down. A pass on a different method is not evidence about yours.<\/p>\n\n\n\n

      If the same part is replaced on every visit, put it on the spare-parts plan. If the instrument fails between visits for a new reason, that is a corrective call, and the preventive interval may need to change.<\/p>\n\n\n\n

      Mahut builds these programs in Oman around the instruments you actually run. To set one up, book a consultation or email info@mahutqc.com with the model list and how many days a week each system runs.<\/p>\n","protected":false},"excerpt":{"rendered":"

      A practical account of what Mahut checks on an HPLC or GC during preventive maintenance, which consumables are replaced, and what the visit does not include.<\/p>\n","protected":false},"author":2,"featured_media":1074,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[25],"tags":[],"class_list":["post-1081","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-educational"],"acf":[],"_links":{"self":[{"href":"https:\/\/pro-studio.ir\/mahutco\/wp-json\/wp\/v2\/posts\/1081","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pro-studio.ir\/mahutco\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pro-studio.ir\/mahutco\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pro-studio.ir\/mahutco\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pro-studio.ir\/mahutco\/wp-json\/wp\/v2\/comments?post=1081"}],"version-history":[{"count":0,"href":"https:\/\/pro-studio.ir\/mahutco\/wp-json\/wp\/v2\/posts\/1081\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pro-studio.ir\/mahutco\/wp-json\/wp\/v2\/media\/1074"}],"wp:attachment":[{"href":"https:\/\/pro-studio.ir\/mahutco\/wp-json\/wp\/v2\/media?parent=1081"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pro-studio.ir\/mahutco\/wp-json\/wp\/v2\/categories?post=1081"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pro-studio.ir\/mahutco\/wp-json\/wp\/v2\/tags?post=1081"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}